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Alpha Lipoic Acid

— alpha Lipoic Acid, Lipoic Acid, Thioctic acid
Product Category: Pharmaceutical Chemicals
Sales Method: Export
Payment Term: T/T
Min. Order Unit Price
Contact Info

Mr.Aaron Liu

Address: China (mainland) Shanghai Shanghai,11-502 Lane 299, Bisheng Rd.

Product Detail

Product Attribute:

  • China (mainland) More >
  • 1077-28-7
  • 04/03/2012
  • 04/05/2012

Additional Info.:

  • Shanghai

Product Content Description:

alpha Lipoic Acid

IUPAC name: (R)-5-(1,2-dithiolan-3-yl)pentanoic acid
Synonyms: DL-Thioctic acid; DL-6,8-Dithiooctanoic acid; 5-(Dithiolan-3-yl)valeric acid; α-lipoic acid; thioctic acid; 6,8-dithiooctanoic acid
C.A.S #:1077-28-7
Molecular formula: C8H14O2S2
Molecular weight : 206.33
Melting point: 58-63°C
Boiling point: 160-165°C

Alpha-Lipoic acid contains not less than 99.0 percent and not more than 101.0 percent of C8H14O2S2,calculated on the dried basis.
Characteristic: Yellow crystalline powder, almost tasteless.

Quality Standards: USP30;
Assay: 99.00% Min. (by HPLC);
Cyclohexane: 0.388% Max ;
Specific Optical Rotation(C=1, Ethanol): +110~+120°;
Loss on Drying: 0.5% Max ;
Residue on Ignition: 0.1% Max ;
Heavy Metals: 10ppm Max ;
Water solubility: Soluble in benzene, ethanol, ethyl ether, chloroform and other organic solvents, but also soluble in water.

Function and Usage: Α-lipoic acid is a vitamin drugs, limited physical activity in its dextral , basically no physical activity in its L - Lipoic acid, and no side effects. It is always used for acute and chronic hepatitis, liver cirrhosis, hepatic coma, fatty liver, diabetes, Alzheimer's disease ,and applies as an antioxidant health products.

Lipoic acid (LA), also known as α-lipoic acid and alpha lipoic acid (ALA) is an organosulfur compound derived from octanoic acid. LA contains two vicinal sulfur atoms (at C6 and C8) attached by a disulfide bond and is thus considered to be oxidized (although either sulfur atom can exist in higher oxidation states). The carbon atom at C6 is chiral and the molecule exists as two enantiomers R-(+)-lipoic acid (RLA) and S-(-)-lipoic acid (SLA) and as a racemic mixture R/S-lipoic acid (R/S-LA). Only the R-(+)-enantiomer exists in nature and is an essential cofactor of four mitochondrial enzyme complexes. Endogenously synthesized RLA is essential for life and aerobic metabolism. Both RLA and R/S-LA are available as over-the-counter nutritional supplements and have been used nutritionally and clinically since the 1950s for various diseases and conditions. LA appears physically as a yellow solid and structurally contains a terminal carboxylic acid and a terminal dithiolane ring.

Today, R/S-LA and RLA are widely available as over-the-counter nutritional supplements in the United States in the form of capsules, tablets and aqueous liquids, and have been branded as antioxidants. This label has recently been challenged. In Japan, LA is marketed primarily as a "weight loss" and "energy" supplement. The relationships between supplemental doses and therapeutic doses have not been clearly defined. Because lipoic acid is not an essential nutrient, no Recommended Daily Allowance (RDA) has been established.
Delivery Way - Date Of Delivery: 15days

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